Metastatic cancer bone

metastatic cancer bone

Rezumat: Bisphosphonates are effective against the increased bone resorption caused by certain diseases because they inhibit the activity of osteoclasts. In patients who have breast cancer and metastatic bone disease, the bisphosphonate clodronate clodronic acid reduces the frequency of skeletal complications.

Experiments metastatic cancer bone animals and preliminary clinical observations indicate that early clodronate therapy reduces the incidence of new bony metastases in breast cancer.

effect of hpv vaccination and cervical cancer screening in england by ethnicity a modelling study oxiuros tratamiento nitazoxanida

We investigated the effects of clodronate on the incidence and extent of new metastases in patients with breast cancer. METHODS: Between andpatients with primary breast metastatic cancer bone and tumor cells in the bone marrow the presence of which is a risk factor for the development of distant metastases were randomly assigned to receive clodronate at a dose of mg per day orally for two years patients or standard metastatic cancer bone patients.

metastatic cancer bone

The median length of observation was 36 months. All patients in both groups received standard surgical treatment and customary hormonal therapy or chemotherapy.

homeopatie viermi intestinali

RESULTS: Distant metastases were detected in 21 patients in the clodronate group and in 42 patients in metastatic cancer bone control group P Cuvinte cheie: breast cancer, bisphosphonates, adjuvant, clinical trial, clodronate.