The objectives of our study were to analyse the static plantar pressure and functional capacity in children with surgically treated unilateral femoral shaft fractures, 1 month after the metallic implant removal. METHODS: Our study included 24 children with unilateral femoral shaft fracture fracture site contralateral to the dominant leg treated by titanium elastic nailing TEN implants, with the removal of the implant 6 months after initial surgery. The patients were divided into two groups: Group 1 12 patients without inpatient rehabilitation and Group 2 12 patients who attended inpatient rehabilitation. The patients and 12 gender and age-matched healthy controls performed plantar pressure analysis and functional capacity testing 6-min walk test: 6MWT. For patients in Group 1 and 2 the assessments were performed 1 month after the Dysbiosis or sibo implant removal.
Previous studies performed in adult patients have demonstrated that both scheduled second look endoscopy and high dose continuous omeprazole infusion are effective in the prevention of peptic ulcer rebleeding. The aim of this study was to compare the efficacy of these two strategies using esomeprazole for the prevention of rebleeding following primary endoscopic hemostasis in children with peptic ulcers.
The main outcome was to assess the rebleeding rate within 30 days after the initial hemostasis. Methods: consecutive pediatric cases who underwent endoscopic treatment for bleeding peptic ulcers were randomized into two treatment groups following hemostasis.
The first group received esomeprazole as an intravenous bolus every 12 hours for 72 hours and a routine second look endoscopy within hours with endotherapy retreatment in the case of dysbiosis or sibo persistent stigmata of bleeding. The second group received a continuous high dose esomeprazole infusion for 72 hours without dysbiosis or sibo reassessment unless required due to rebleeding.
Results: a total of 63 children were randomized to the second look endoscopy group and 64 to the esomeprazole infusion group. Rebleeding occurred within 30 days in four patients 6.
Day 4 - FMT - Fecal Transplant - Dysbiosis/Candida/Sibo/IBS
Conclusions: a pharmaceutical approach using a high dose continuous esomeprazole infusion in dysbiosis or sibo after an initial endoscopic hemostasis has a similar efficacy compared to second look endoscopy and bolus esomeprazole administration for the prevention of peptic ulcer rebleeding.