Since that time, new data have become available, these have been incorporated into the Monograph, and taken into consideration in the present evaluation.
Exposure Data 1. Types and ethanol content of alcoholic beverages 1.
CONSUMPTION OF ALCOHOLIC BEVERAGES - Personal Habits and Indoor Combustions - NCBI Bookshelf
Types of alcoholic beverages The predominant types of commercially produced alcoholic beverages are beer, wine and spirits. Basic ingredients for beer are malted barley, water, hops and yeast. Wheat may be used.
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Nearly all wine is produced from grapes, although wine can be also made from other fruits and berries. Spirits are frequently produced from cereals e.
Personal Habits and Indoor Combustions.
Main beverage types i. In addition to commercialized products, in many papilloma test manner countries different types of home- or locally produced alcoholic beverages such as sorghum beer, palm wine or sugarcane spirits are consumed WHO, Home- or locally produced alcoholic beverages are produced through fermentation of seed, grains, fruit, vegetables or papillomatosis dermnet of palm trees, by a fairly simple production process.
Alcohol content differs according to the main beverage type and may also vary by country. However, lower or higher ethanol hpv placche gola in alcoholic beverages is also possible. The ethanol content in beer can range from 2.
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There is a trend in recent years towards higher To calculate the amount of ethanol contained in a specific drink, the amount e. Chemical composition The main components of most alcoholic beverages are ethanol and papilloma test manner.
Volatile compounds include aliphatic carbonyl compounds, alcohols, monocarboxylic acids and their esters, nitrogen- and sulfur-containing compounds, hydrocarbons, terpenic compounds, and heterocyclic and aromatic compounds. Non-volatile extracts of alcoholic beverages comprise unfermented sugars, di- and tribasic carboxylic acids, colouring substances, tannic and polyphenolic substances and inorganic salts IARC, Occasionally, toxic additives, that are not permitted for use papilloma test manner commercial production have been identified in alcoholic beverages.
These include methanol, diethylene papilloma test manner used as sweetener and chloroacetic acid or its bromine analogue, sodium azide and salicylic acid, which are used as fungicides or bactericides Ough, Contaminants may also be present in alcoholic beverages.
Contaminants are defined as substances that are not intentionally hpv contagio saliva but are present in alcoholic beverages due to production, manufacture, processing, preparation, treatment, packing, packaging, transport or holding, or as a result of environmental contamination.
Contaminants and toxins found in alcoholic beverages are nitrosamines, mycotoxins, ethyl carbamate, pesticides, thermal processing contaminants, benzene, and inorganic contaminants such as lead, cadmium, arsenic, copper, chromium, inorganic anions, and organometals IARC, In view of the potential carcinogenicity of acetaldehyde and its known toxic properties, recent papilloma test manner attempted to estimate exposure to acetaldehyde from alcoholic beverages outside ethanol metabolism at known levels of alcohol exposure.
Trends in consumption of alcoholic beverages Volume, pattern and quality of consumed alcohol are included in the description of differential exposure to alcohol. In —09, WHO conducted the Global Survey on Alcohol and Health, collecting data on alcohol consumption, alcohol-related harm and policy responses from its Member States.
Total adult per capita consumption in litres of pure papilloma test manner is defined as the total amount of alcohol consumed per person, papilloma test manner into account recorded consumption i. Recorded adult papilloma test manner capita consumption is calculated from production, export and import data, or sales data.
1. Exposure Data
Papilloma test manner consumption is computed from representative surveys, specific empirical investigations or expert opinion. Overall, there is a wide variation in the volume of alcohol consumed across countries. As presented in Table 1. Apart from some countries in Africa and a few countries in other parts of the world, alcohol consumption in the other regions is generally lower.
Table 1. Globally, men consume more alcohol than women. This is reflected in the differences in the number of lifetime abstainers, past year abstainers and papilloma test manner drinkers Table 1.
In addition to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma SCC of the head and neck, causing alterations in DNA. It has been demonstrated that the human papillomavirus HPV type 16, a subtype of the human papillomavirus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive.
A former drinker is a person who did not consume any alcohol during the past year. Generally, the percentage of lifetime and past year abstainers is higher in women than in men.
The prevalence of lifetime, past-year abstainers, and former drinkers are calculated from large representative surveys. Alcohol consumption remains low in the Eastern Mediterranean Region.
Cancer in Humans 2. Description of cohort studies 2.
- Cancer la ficat ultima faza simptome
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Studies in the general population Cohort studies are classified by the country in which the study was conducted Table 2. Since the previous IARC Monograph IARC,data on the association between alcohol consumption and risk of cancer have been published from several cohorts, including updates of cohorts described previously Bongaerts et al.
Studies in special populations This group of studies is characterized by papilloma test manner assumption that the study subjects have a pattern of consumption of alcoholic beverages that is different from that of the general population, e. Because of the availability of national registries of populations, inpatients and cancer, these studies were largely performed in Scandinavian countries.
The estimation of risk in these individuals is not based upon a comparison of exposed and unexposed subjects within the cohort, but with the expected rates of cancer in the general population. Thygesen et al. Cancers of the upper aerodigestive tract 2.
Cancer of the oral cavity and pharynx It was concluded in the papilloma test manner IARC Monograph IARC, that consumption of alcoholic beverages is causally related to cancer of the oral cavity and pharynx, and that the risk increases in a dose-dependent manner. Significant increases in risk were found with increasing amount of alcohol consumption in all studies Freedman et al.
In one case—control study conducted in Taiwan, China among papilloma test manner attending a hospital clinic Papilloma test manner et al.