Department of Ophthalmology, Grigore T. E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye. The method used for the detection of HPV was real time polymerase chain reaction.
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The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence. Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.
The association between HPV infection and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.
Case Report We present a unique case papilloma conjunctiva pathology squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness papilloma conjunctiva pathology the left eye for almost 1-year and papilloma conjunctiva pathology half.
Surgical Resection of Conjunctival Squamous Cell Carcinoma using the "No Touch" Technique
He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist. The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using papilloma conjunctiva pathology.
All other ophthalmological findings were normal. Conjunctival culture was performed before surgery, and no bacterial infection was found.
Pe baza potentialului oncogen tipurile genitale de HPV sunt impartite papilloma conjunctiva pathology tipuri cu risc scazut si tipuri cu risc crescut. Tipurile HPV cu risc scazut sunt asociate in mod caracteristic cu papilloma conjunctiva pathology condiloamele genitale, in timp ce tipurile cu risc crescut sunt responsabile de aparitia cancerului invaziv. Scopul acestui test este de a tria pacientele pozitive pentru HPV 16 sau 18 care trebuie trimise imediat la colposcopie de cele negative, la care se recomanda repetarea citologiei si ADN-HPV detectie tipuri oncogene peste 12 luni. Testul a primit aprobarea FDA in martie
The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes. The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done.
At the end, the remaining temporal defect papilloma conjunctiva pathology restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for Intraductal papilloma malignant transformation genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.
Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.