It is known as a heterogeneous disease, characterized by diversion in multiple molecular pathways during its evolutionary process. Being an integral part of a wider study, we explored the use of a rectal cancer history platform to support the strictly controlled process of data collection on colorectal cancer cases. We collected data about the patients regarding baseline rectal cancer history parameters, medical history, important comorbidities, intraoperative findings and adverse events, tumor characteristics, histological findings and main laboratory data blood rectal cancer history count, serum protein electrophoresis, liver and kidney function tests, serum levels of CEA and CA The results suggest that these two biomarkers are useful preoperative indicators of local recurrences and prognosis in colorectal cancer.
Increased levels of both tumor markers are correlated with an advanced stage of the disease and a poor prognosis. Finally, this study aims to provide the necessary infrastructure, geared towards efficient, safe and comprehensive clinical evaluation of CRC cases.