Department of Ophthalmology, Grigore T. E-mail: moc.
The clinical color photographs for the most part are of fine quality. The histology is shown side by side with the clinical findings. Shaded summary boxes highlight the salient points for those who wish a quick read through the book Everyone will enjoy the thorough coverage of the diagnosis and management of skin cancer in this book. I highly recommend it be purchased by any physician caring for patients with skin cancer.
We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.
The method used for the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence.
Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.
The association between HPV infection and eye tumors is little explored territory.
Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.
Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.
He has been treated for the last 2 months hpv cause skin cancer dexamethasone eye drops for scleritis by another ophthalmologist.
The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses. All other ophthalmological findings were normal.
Melanomul este cea mai severă formă de cancer cutanat. Melanomul poate apărea oriunde pe suprafaţa pielii, incusiv pe zonele care nu sunt expuse la soare, dar este mai probabil să apară în anumite zone. Este una din cele mai frecvent întâlnite forme de cancer la tineri adulţi, în special femei.
Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan of hpv cause skin cancer head and neck showed no signs of tumor invasion of the orbit or the lymph nodes.
The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was hpv cause skin cancer into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR hpv cause skin cancer and refrigerated at 4°C until processing.
Histopathology exam showed a hpv cause skin cancer differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.