Ovarian cancer journal article.

ovarian cancer journal article

Could bilateral salpingectomy reduce the risk of ovarian cancer?

Could bilateral salpingectomy reduce the risk of ovarian cancer?

Epithelial ovarian cancer is the fifth leading cause of cancer mortality among women. There is no effective screening for ovarian cancer in the current practice that could decrease its mortality.

There is a large volume of scientific proofs that prophylactic salpingectomy could give the clinicians the opportunity to prevent the development of ovarian cancer.

The goal of our paper is to sensitize the gynecologic community and then ovarian cancer journal article study ovarian cancer journal article a prospective national trial the potential use of prophylactic bilateral salpingectomy as a primary preventive strategy of the ovarian cancer.

Currently, we have no prospective evidence in order to analyze the effectiveness of prophylactic bilateral salpingectomy in preventing ovarian cancer.

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Through this article, we intend to launch an invitation to all Romanian gynecologic surgery centers, to participate in a prospective study evaluating the effectiveness of bilateral salpingectomy in the prevention of ovarian cancer.

Materials and method. There is no strong evidence regarding ovarian cancer journal article effectiveness of bilateral salpingectomy in the prevention of ovarian cancer and this is the first multicenter, prospective trial in order to study this hypothesis.

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Using this journal and other media channels of the Romanian Society of Obstetrics and Gynecology, we want to invite national centers of obstetrics and gynecology to attend to our study. The deadline for the approval is 1st of May The patients will be consecutively selected from a general population who undergo a surgical procedure during which the fallopian tubes could be removed in addition to the primary surgical procedure.

All data needed regarding the patient and the procedure will be collected in an online document and kept into the database of the department. The enrollment period will be from 1st of June till May 30th Endometrial cancer protective factors 1st of August all the data must be collected and prepared for publication.

The effectiveness of bilateral salpingectomy in the prevention of ovarian cancer will be evaluated according to multiple variables.

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Keywords bilateral salpingectomy, ovarian cancer, ovarian cancer prevention Rezumat Introducere. Cancerul ovarian epitelial reprezintă a cincea cauză de mortalitate prin cancer în rândul femeilor.

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Nu există nicio metodă eficientă de screening pentru cancerul de ovar care să scadă mortalitatea. Salpingectomia profilactică poate oferi oportunitatea de prevenție a apariției cancerului ovarian.

Once successful, these could be of value to women struggling with infertility or cancer patients who cannot conceive after undergoing radiation or chemotherapy.

Studiul nostru are scopul de a invita comunitatea de specialitate în vederea participării la un trial prospectiv național, care să studieze rolul potențial al salpingectomiei bilaterale profilactice ca strategie de prevenție primară a cancerului ovarian. În momentul actual, nu deținem date prospective care să analizeze eficacitatea salpingectomiei bilaterale profilactice ca metodă de prevenție a cancerului ovarian.

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  • Poate salpingectomia bilaterală reduce riscul de cancer ovarian?

Ovarian cancer journal article intermediul acestui articol, intenționăm să lansăm o invitație centrelor de chirurgie ginecologică din România pentru a participa la un studiu prospectiv care să evalueze eficacitatea salpingectomiei bilaterale în prevenția cancerului ovarian. Materiale și metodă. Nu există evidențe valide cu privire ovarian cancer journal article eficacitatea salpingectomiei bilaterale profilactice în prevenția cancerului ovarian, acesta reprezentând primul trial prospectiv, multicentric care studiază această ipoteză.

ARS Medica Tomitana Volume 24 Issue 2 ()

Prin intermediul revistei, precum și al altor canale media ale Societății Române de Obstetrică și Ginecologie, intenționăm să invităm centrele naționale de obstetrică și ginecologie să participe la studiul nostru. Toate centrele necesită avizul comisiei de etică, precum și aprobarea unui consimțământ informat adaptat studiului. Termenul stabilit pentru aprobare este 1 mai Selecția pacientelor se realizează din populația generală, paciente supuse unei proceduri chirurgicale, în timpul căreia se poate realiza salpingectomia bilaterală profilactică, adițional intervenției principale.

Toate datele vor fi colectate prin intermediul unui formular online și centralizate într-o bază de date. Perioada de înrolare a pacientelor va fi începând cu 1 iunie și până pe 30 mai Până pe 1 august toate datele trebuie centralizate și pregătite spre a fi publicate.

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Eficacitatea salpingectomiei bilaterale profilactice în prevenția cancerului ovarian va fi evaluată în funcție de mai multe variabile. Cuvinte cheie salpingectomie bilaterală cancer ovarian prevenția cancerului ovarian Introduction Ovarian cancer has the poorest prognosis and limited options in terms of early diagnosis and efficient treatment. There ovarian ovarian cancer journal article journal article no effective screening methods to prevent ovarian cancer in order to decrease mortality rate.

New theories in carcinogenesis suggest that ovarian high-grade serous carcinoma develops from the distal fallopian tube epithelium 1. Opportunistic bilateral salpingectomy during hysterectomy or other gynecological surgery has a minimal additional surgical risk to the patient.

ovarian cancer journal article

For this reasons, in our clinic we adopted this prophylactic surgical procedure in patients eligible for hysterectomy to treat benign conditions, with no complication or intraoperative incidences. All the patients were counseled about the potential benefits of the removal of the fallopian tubes in order to decrease the risk of ovarian cancer.

Morelli et al. A larger long-term study is needed to assess the prophylactic role of opportunistic bilateral salpingectomy and its implications in ovarian cancer development.

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Materials and method We propose a national, multicenter, prospective, descriptive non-randomized interventional trial in order to evaluate the prophylactic role of opportunistic bilateral salpingectomy in reducing the risk of developing ovarian carcinoma.

The aim of our multicenter trial is to analyze the potential use of bilateral salpingectomy as a primary preventive strategy of the ovarian cancer. The study will be in accordance with the Committee on Publication Ethics guidelines and will be approved by the institutional review board of each hospital that will join the project.

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Each ovarian cancer journal article who will participate in this study will be well informed regarding the procedures and will sign a consent form for data collection for research purposes.

An independent data safety and monitoring committee will evaluate the results ovarian cancer journal article the study. All women candidates for different surgical gynecological interventions for benign reasons hysterectomy, ovarian cystectomy, tubal ligation or caesarean section, with requested voluntary tubal ligation, will be enrolled after a previous counseling with the potential benefits and fertility consequence of the method.

After bilateral salpingectomy, all women will perform clinical and transvaginal ultrasound examination annually for 3 consecutive years. All data regarding the patient and the procedure will be collected in a document ovarian cancer journal article the D-Base designed for this purpose.

Material and method: The study has included women diagnosed with ovarian cancer. The most frequent risk factor for serous type was the ovulation lifetime over 30 years

We will exclude from the enrollment women with malignant and borderline diseases, even in cases when the diagnosis was established intraoperatively or later histopathological specimen. Also, will be excluded patients that do not agree to sign the informed consent.

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